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- Title
The role of exercise on the innate immunity of the elderly.
- Authors
Malaguarnera, Lucia; Cristaldi, Erika; Vinci, Maria; Malaguarnera, Mariano
- Abstract
The increased life span in human population has shown that some diseases, as infections, cancer and autoimmune phenomena, occur more frequently in the elderly than in the younger. We describe the ageing process involving the innate immune system and the improvement given by moderate physical activity. In addition, we discuss the altered neutrophil granulocytes function, the role of macrophages and natural killer cells, besides the influence of cytokines and secretory IgA. The acquired information help us to explain how these changes could favor the onset of diseases in the elderly and how they may boost their immune function.
- Subjects
EXERCISE for older people; PHYSICAL fitness; HEALTH; AGING; IMMUNOSENESCENCE; NEUTROPHILS; GRANULOCYTES; CYTOKINES; CELLULAR immunity
- Publication
European Reviews of Aging & Physical Activity, 2008, Vol 5, Issue 1, p43
- ISSN
1813-7253
- Publication type
Article
- DOI
10.1007/s11556-007-0028-8