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- Title
The effects of small-needle-knife therapy on pain and mobility from knee osteoarthritis: a pilot randomized-controlled study.
- Authors
Zhu, Junchen; Zheng, Zhiwen; Liu, Yaomeng; Lawrie, Sophie; Esser, Patrick; Izadi, Hooshang; Dawes, Helen; Xia, Zhidao; Wang, Chao; Xiong, Yingzong; Ma, Xingfu; Wade, Derick T
- Abstract
Objective: To investigate the effect of small needle-knife therapy in people with painful knee osteoarthritis. Design: Pilot randomised, controlled trial. Setting: Rehabilitation hospital. Subjects: In-patients with osteo-arthritis of the knee. Interventions: Either 1 to 3 small needle-knife treatments over seven days or oral Celecoxib. All patients stayed in hospital three weeks, receiving the same mobility-focused rehabilitation. Measures: Oxford Knee Score (OKS), gait speed and kinematics were recorded at baseline, at three weeks (discharge) and at three-months (OKS only). Withdrawal from the study, and adverse events associated with the small needle knife therapy were recorded. Results: 83 patients were randomized: 44 into the control group, of whom 10 were lost by three weeks and 12 at 3 months; 39 into the experimental group of whom eight were lost at three weeks and three months. The mean (SE) OKS scores at baseline were Control 35.86 (1.05), Exp 38.38 (0.99); at three weeks 26.64 (0.97) and 21.94 (1.23); and at three months 25.83 (0.91) and 20.48 (1.14) The mean (SE) gait speed at baseline was 1.07 (0.03) m/sec (Control) and 0.98 (0.03), and at three weeks was 1.14 (0.03) and 1.12 (0.03) (P < 0.05). Linear mixed model statistical analysis showed that the improvements in the experimental group were statistically significant for total OKS score at discharge and three months Conclusions: Small needle-knife therapy added to standard therapy for patients with knee osteoarthritis, was acceptable, safe and reduced pain and improved global function on the Oxford Knee Score. Further research is warranted.
- Subjects
ACUPUNCTURE; COMPARATIVE studies; KINEMATICS; KNEE diseases; NONSTEROIDAL anti-inflammatory agents; OSTEOARTHRITIS; RESEARCH funding; STATISTICAL sampling; STATISTICS; PAIN management; CYCLOOXYGENASE 2; PILOT projects; DATA analysis; RANDOMIZED controlled trials; TREATMENT effectiveness; PRE-tests &; post-tests; DATA analysis software; DESCRIPTIVE statistics; WALKING speed; PHYSICAL mobility
- Publication
Clinical Rehabilitation, 2020, Vol 34, Issue 12, p1497
- ISSN
0269-2155
- Publication type
Article
- DOI
10.1177/0269215520938852