We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Production of paclitaxel by Fusarium solani isolated from Taxus celebica.
- Authors
Chakravarthi, B. V. S. K.; Das, Prasanta; Surendranath, Kalpana; Karande, Anjali A.; Jayabaskaran, Chelliah
- Abstract
A fungus was isolated from the stem cuttings of Taxus celebica, which produced paclitaxel in liquid-grown cultures. The fungus was identified as Fusarium solani based on colony characteristics, morphology of conidia and the 26S rDNA sequence. Paclitaxel was identified by chromatographic and spectroscopic comparison with authentic paclitaxel and its cytotoxic activity towards Jurkat cells in vitro.
- Subjects
PACLITAXEL; FUSARIUM solani; NUCLEOTIDE sequence; CHROMATOGRAPHIC analysis; SPECTRUM analysis; ANTINEOPLASTIC agents
- Publication
Journal of Biosciences, 2008, Vol 33, Issue 2, p259
- ISSN
0250-5991
- Publication type
Article
- DOI
10.1007/s12038-008-0043-6