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- Title
Successful Diagnosis and Treatment of Occult Prostate Cancer Despite Multiple Negative Prostate Biopsies and Negative Prostate MRIs.
- Authors
Morris, Kostantinos E.; Grimberg, Dominic C.; Gupta, Rajan T.; Pendse, Avani A.; Moul, Judd W.
- Abstract
Prostate-specific antigen (PSA) values above 100 ng/mL often suggest metastatic prostate cancer. We present the case of a patient with a PSA of 110 ng/mL, 4 negative prostate biopsies, and 4 negative prostate MRIs. After his fifth MRI revealed a PI-RADS 5 lesion, he underwent his fifth transrectal biopsy; this revealed Gleason 3 + 4 = 7. He was found to have organ-confined pT2 disease on subsequent radical prostatectomy pathology. This case highlights that there may be no PSA for which one can assume metastatic disease with certainty. Depending on life expectancy, patients with extremely elevated PSA may still warrant a full staging workup.
- Subjects
DELAYED diagnosis; BIOPSY; RADICAL prostatectomy; MAGNETIC resonance imaging; DIAGNOSTIC errors; PROSTATE-specific antigen; PROSTATE tumors
- Publication
Oncology (08909091), 2022, Vol 36, Issue 3, p178
- ISSN
0890-9091
- Publication type
Article