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- Title
Effects of amino acid supplementation on muscle mass, muscle performance and functional capacity in subjects undergoing total knee arthroplasty: a systematic review of randomized clinical trials.
- Authors
de Souza Borges, Jose Humberto; Junior, Paulo Lobo; de Brito, Felipe Fagundes; Rezende, Heitor Paes; de Souza Silva, Marcos Vinicius; Oliveira, Marcio; Barin, Fabrício Reichert
- Abstract
The aim of the present study was to summarize the effectiveness of amino acid supplementation on muscle strength, muscle volume, and functional capacity in patients undergoing total knee arthroplasty. For this, in November 2022, a search was carried out in the PubMed, Cochrane Library, and EMBASE databases, identifying a total of 2182 documents, of which only 4 were included in the present review. The included studies had 148 participants (47 men and 101 women), with a minimum age of 53 and a maximum of 92 years, and supplementation times of 13 to 30 days (1 to 3 times a day). For the results, in relation to muscle performance, when comparing the control and experimental groups, greater muscle atrophy was observed in the pre- and post-moments of the control group, in relation to the experimental group. In addition, studies suggest a good tendency for muscle mass gain, and improvement in the functional capacities of patients who used supplementation. Therefore, the use of amino acids after TKA surgery reduces muscle atrophy, which preserves muscle mass and leads to better performance in tests of strength and functional capacity, when compared to the use of a placebo.
- Subjects
MEDICAL information storage &; retrieval systems; SKELETAL muscle; FUNCTIONAL status; MUSCLE strength; SYSTEMATIC reviews; MEDLINE; AMINO acids; TOTAL knee replacement; MEDICAL databases; BODY movement; ONLINE information services; QUADRICEPS muscle; DIETARY supplements; ISOKINETIC exercise
- Publication
European Journal of Orthopaedic Surgery & Traumatology, 2024, Vol 34, Issue 3, p1717
- ISSN
1633-8065
- Publication type
Article
- DOI
10.1007/s00590-023-03824-3