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- Title
Fungal Dehydrogenation and Oxidative Acyl Group Cleavage of Dydrogesterone by Using Aspergillus flavus, and Their Comparative Antimicrobial Studies.
- Authors
Azizuddin; Iqbal, M.
- Abstract
This article, published in Chemistry of Natural Compounds, explores the use of fungi to produce fine chemicals through whole cell cultures. The researchers specifically focus on the transformation of the fertility agent Dydrogesterone (DYD) using the fungus Aspergillus flavus. They provide spectroscopic data for the compounds formed during this transformation and conduct antimicrobial bioassays. The article highlights the potential of fungi in modifying steroidal and non-steroidal compounds and suggests the need for further research in this area. The study found that A. flavus was able to transform DYD into various products, and the antifungal activity of these products was tested against different fungi and bacteria. The document also provides details on the experimental methods used in the study.
- Subjects
ACYL group; OXIDATIVE dehydrogenation; ASPERGILLUS flavus; THIN layer chromatography; MICROBIAL metabolites; SODIUM sulfate; POTASSIUM dihydrogen phosphate
- Publication
Chemistry of Natural Compounds, 2024, Vol 60, Issue 3, p573
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-024-04385-5