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- Title
Hepatoprotective Phenylpropanoid Glycosides from Highland Barley Monascus purpureus.
- Authors
Wei, Rongrui; Wang, Qinyuan; Lin, Qingyuan; Jiang, Xianbao; Zhang, Zhongli; Cao, Lan; Guo, Jiazeng; Ma, Qinge
- Abstract
A new phenylpropanoid glycoside, named 4-O-β-D-glucopyranosyl-7-phenyl-9-propenyl ketone-9-O-β-Dglucopyranosyl-(6′′→1′′′)-6′′-O-α-L-rhamnopyranose (1), and four known phenylpropanoid glycosides 2–5 were isolated from highland barley Monascus purpureus Went for the first time. Their structures were determined by their comprehensive spectral data and reported references. Compounds 1–5 were evaluated for their hepatoprotective activities against D-galactosamine-induced toxicity in WB-F344 cells with bicyclol as positive control. As a result, compounds 1 and 2 exhibited moderate hepatoprotective activities.
- Subjects
MONASCUS purpureus; PHENYLPROPANOIDS; BARLEY; UPLANDS; GLYCOSIDES
- Publication
Chemistry of Natural Compounds, 2024, Vol 60, Issue 1, p45
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-024-04250-5