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- Title
Synthesis of symmetric macrocyclic diesterdihyrazides using successive [2+1]- and [1+1]-condensations.
- Authors
Ishmuratov, G. Yu.; Mingaleeva, G. R.; Yakovleva, M. P.; Muslukhov, R. R.; Vyrypaev, E. M.; Ivanov, S. P.; Tolstikov, A. G.
- Abstract
Potentially useful symmetric macrocyclic diesterdihydrazides were synthesized efficiently from available petrochemical products (tetrahydropyran and 4-methyltetrahydropyran) using successive [2+1]-condensation of 8-hydroxyoctan-2-one and its 6-methyl derivative with glutaric and adipic chlorides and [1+1]-condensation of the intermediate diketodiesters with glutaric dihydrazide.
- Subjects
MACROCYCLIC compounds; PETROLEUM chemical research; PETROLEUM products reserves; CHLORINE compounds; CONDENSATION; BIOCHEMISTRY
- Publication
Chemistry of Natural Compounds, 2010, Vol 46, Issue 1, p10
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-010-9513-9