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- Title
Frequency of Vitamin B12 Deficiency and Associated Findings in Children .
- Authors
AYDIN, Hilal; KORKUT, Oğuzhan; ÖZDEN, Ezgi; CAN, Demet
- Abstract
Objective: The purpose of this study was to determine clinical findings associated with vitamin B12 deficiency in patients presenting to the pediatric neurology department with various different symptoms and to discuss these in the light of the current literature. Materials and Methods: Children aged between one month and 18 years presenting to the Balikesir University Medical Faculty pediatric neurology clinic, Turkey, between 01.08.2019-01.08.2021 and with vitamin B12 levels lower than 250 ng/mL were included in this retrospective, cross-sectional study. Results: One hundred sixty-one cases were included in the study 63 (39.1%) female and 98 (60.9%) male. The patients’ mean age was 7.43±5.77 (0-17) years. The majority of patients of both genders were in the 0-6 age group. Neurological findings were present in 81.98% of patients with Vitamin B12 deficiency, and non-neurological findings in 18.02%. The most frequent neurological finding was neuromotor retardation (N=73, 45.34%), followed by seizures (N=33, 20.50%). The mean Vitamin B12 level among all the patients was 167.70±45.17 (58-250) pg/ml. No statistically significant difference was determined between boys and girls in terms of Vitamin B12 and ferritin levels or complete blood count parameters [Hb, Htc, and MCV] (respectively p=0.428, p=0.646, p=0.110, p=0.128, p=0.864). Conclusions: This study provides a general evaluation for health professionals regarding clinical presentations encountered by us in association with the disease.
- Subjects
TURKEY; ACADEMIC medical centers; VITAMIN B12; MANN Whitney U Test; RETROSPECTIVE studies; NEUROLOGIC manifestations of general diseases; T-test (Statistics); DESCRIPTIVE statistics; SEIZURES (Medicine); DATA analysis software; VITAMIN B12 deficiency; SYMPTOMS; CHILDREN; ADOLESCENCE
- Publication
Balikesir Health Sciences Journal / Balıkesir Sağlık Bilimleri Dergisi, 2022, Vol 11, Issue 3, p503
- ISSN
2146-9601
- Publication type
Article
- DOI
10.53424/balikesirsbd.1142063