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- Title
Green synthesis of zinc oxide nanoparticles using the plant extract of Myristica fragrans and their antibacterial activity assessment.
- Authors
DASH, Priyanka; GOCHHI, Monalisa; GHOSH, Goutam
- Abstract
BACKGROUND: Zinc nanoparticles (Zn-NPs) are useful for targeting specific tissues and pathogenic bacteria, which has attracted many researchers to their green manufacture and applications. METHODS: In the current study, Myristica fragrans aqueous seed extracts were used to synthesize zinc oxide nanoparticles (ZnO-NPs). Solution combustion synthesis (SCS) was used to generate useful zinc oxide nanoparticles (ZnO-NPs). Different methods were used to characterize the ZnO-NPs, including X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), elemental dispersion analysis of X-rays (EDX) and Transmission electron microscopy (TEM). Viable cell count and the broth-based turbidometry method were used to assess the antibacterial efficacy of green synthesized ZnO-NPs against three Gram-negative and two Gram-positive pathogens. RESULTS : The results of both the assay showed that the Zn nanoparticle from M. fragrans has significant highest antibacterial activity against P. aeruginosa and B. subtilis. CONCLUSIONS: As a result, the study suggests that Zn-NPs have potent antibacterial action and could be developed as a new class of antimicrobial drugs for the treatment of infections, particularly those that are resistant to several drugs.
- Subjects
NUTMEG tree; ZINC oxide synthesis; PLANT extracts; ANTIBACTERIAL agents; SELF-propagating high-temperature synthesis; ZINC oxide
- Publication
Minerva Biotechnology & Biomolecular Research, 2023, Vol 35, Issue 2, p81
- ISSN
2724-542X
- Publication type
Article
- DOI
10.23736/S2724-542X.23.02957-7