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- Title
Bacterial therapy and mitochondrial therapy.
- Authors
Popkov, V.; Plotnikov, E.; Silachev, D.; Zorova, L.; Pevzner, I.; Jankauskas, S.; Zorov, S.; Andrianova, N.; Babenko, V.; Zorov, D.
- Abstract
Current methods for treatment of cellular and organ pathologies are extremely diverse and constantly evolving, going beyond the use of drugs, based on chemical interaction with biological targets to normalize the functions of the system. Because pharmacological approaches are often untenable, recent strategies in the therapy of different pathological conditions are of particular interest through introducing into the organism of some living system or its components, in particular, bacteria or isolated subcellular structures such as mitochondria. This review describes the most interesting and original examples of therapy using bacteria and mitochondria, which in perspective can dramatically change our views on the principles for the treatment of many diseases. Thus, we analyze such therapeutic effects from the perspective of the similarities between mitochondria and bacteria as the evolutionary ancestors of mitochondria.
- Subjects
THERAPEUTIC use of bacteria; TOXICOLOGICAL interactions; MITOCHONDRIA; TREATMENT effectiveness; THERAPEUTICS
- Publication
Biochemistry (00062979), 2017, Vol 82, Issue 12, p1549
- ISSN
0006-2979
- Publication type
Article
- DOI
10.1134/S0006297917120148