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- Title
咼效液相色谱一串联质谱法测定食品塑料 包装材料中双酚A和壬基酚.
- Authors
唐吉旺; 袁列江; 肖泳; 王淑霞; 潘照; 邓航
- Abstract
Objective; A method based on high-performance liquid chromatography-mass spectrometry was developed for the simultaneous determination of bisphenol A and nonylphenol in food packaging material. Methods: The extraction solvent and extraction method were investigated. Solid-phase extraction (SPE) conditions were optimized. The effects of solid phase extraction column, loading solvent, eluting solvent and elution solvent on the purification effect were systematically analyzed. The samples were ultrasonic extracted with dichloromethaneand cleaned up on a solid-phase extraction (SPE) cartridge equipped with packing material of silicone. The separation was performed on a Venusil MP Cis(2)(100 mmX2.1 mm,2.6 pm)by gradient elution with 0.1% ammonia solution and methanol as mobile phase. The analytes were determined with multiple reaction monitoring (MRM) mode under electrospray negative ionization mode and quantified by an internal standard method. Results: The results indicated that good linearities was obtained for bisphenol A and nonylphenol both within the concentration range of 1.0 ~ 200.0 pg/L. The average recoveries of each analyte at three spiked levels of 1.0, 10.0, 200.0 pg/kg were in the range of 89.2%~~101.2%, with relative standard deviations (RSD) of 3.1 6. 2%. The limits of detection (LODs) and limits of quantification (LOQs) were 0. 5 pg/kg and 1. 0 pg/kg, respectively. Conclusion: The method was proved to be a simple, accurate and sensitive method and was successfully applied to detect bisphenol A and nonylphenol in food packaging material. It can also provide reference for the determination of bisphenol A and nonylphenol in food.
- Subjects
LIQUID chromatography-mass spectrometry; SOLVENT extraction; PACKAGING materials; FOOD packaging; GRADIENT elution (Chromatography); SOLID phase extraction; BISPHENOL A; NONYLPHENOL
- Publication
Food & Machinery, 2023, Issue 1, p37
- ISSN
1003-5788
- Publication type
Article
- DOI
10.13652/j.spjx.1003.5788.2022.80371