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- Title
Spindle assembly: asters part their separate ways.
- Authors
Rosenblatt, Jody
- Abstract
Cells have developed diverse ways to separate two microtubule asters to form a mitotic spindle. Here, I focus on two mechanisms used to position asters around chromosomes during mitosis: first, aster migration around the nuclear envelope and, second, aster attachment to a contractile cortex at the plasma membrane after the nuclear envelope has broken down. Although certain cell types use one mechanism predominantly, most rely on both to ensure proper spindle assembly.
- Subjects
MEIOSIS; CELL nuclei; CELL division; CELL membranes; CHROMOSOMES; GENETICS
- Publication
Nature Cell Biology, 2005, Vol 7, Issue 3, p219
- ISSN
1465-7392
- Publication type
Article
- DOI
10.1038/ncb0305-219