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- Title
The Morphological Aspects of Neovaginoplasty Using Oxidized Cellulose Membrane (Interceed<sup>®</sup>).
- Authors
Crema, Luciana; Jármy Di-Bella, Zsuzsanna; Takano, Claudia; Castro, Rodrigo; Simões, Manuel de Jesus; Ferreira Sartori, Marair Gracio; Batista Castello Girão, Manoel João
- Abstract
Objective: The purpose of this study was to evaluate the postoperative morphologic aspects of neovaginoplasty by the McIndoe technique with the use of an oxidized cellulose membrane (Interceed®) - an absorbable adhesion barrier - to correct congenital vaginal defects. Design: This study was designed as a prospective study. Patients and Methods: The sample consisted of 10 patients treated at the Department of Urogynecology, Federal University of São Paulo, 7 patients with Mayer-Rokitansky-Küster-Hauser Syndrome, and 3 patients with congenital vaginal atresia. In order to evaluate the epithelization process, monthly biopsies for the first 3 months and then on the 9th month after neovaginoplasty using Interceed, were collected. Results: In all patients, lamina propria rich in blood vessels and epithelioid cells were found in a vaginal fragment after 1 month of the neovaginoplasty. Typical vaginal epithelium was also observed and the reaction for identification of glycogen (PAS) was positive 9 months after surgery in all cases. Conclusions: The oxidized cellulose membrane proved to be a suitable material to use as coating of the neovagina for the correction of congenital defects such as vaginal agenesis. It is possible to obtain a typical vaginal epithelium after the use of this absorbable adhesion barrier. (J GYNECOL SURG 29:169)
- Subjects
BRAZIL; VAGINA abnormalities; VAGINAL surgery; CELLULOSE; LONGITUDINAL method; HEALTH outcome assessment; TREATMENT effectiveness; DESCRIPTIVE statistics; MAYER-Rokitansky-Kuster-Hauser syndrome
- Publication
Journal of Gynecologic Surgery, 2013, Vol 29, Issue 4, p169
- ISSN
1042-4067
- Publication type
Article
- DOI
10.1089/gyn.2011.0098