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- Title
Factors Predicting Mortality in Methyl Alcohol Intoxication: A Retrospective Clinical Trial.
- Authors
Aslan, Murat; Bilgi, Deniz Özel
- Abstract
Objective: Methyl alcohol, which is quite cheap compared to ethyl alcohol, can be used to produce imitated alcohol. For this reason, cases of methyl alcohol intoxication can be observed from time to time. Although it is rare, it is an emergency that needs to be diagnosed and treated early because of its high mortality. Methods: In this study, 22 patients aged ≥18 years who were admitted to the intensive care unit (ICU) due to methyl alcohol intoxication between 2015 and 2022 were included. The patients were divided into 2 groups, survivor and non-survivor, and compared retrospectively in terms of factors predicting mortality. Results: Except for one of the 22 patients included in the study, all patients developed methyl alcohol intoxication because of the use of imitated alcohol. Only one patient had a history of using perfume for suicidal purposes. Of the patients who developed methyl alcohol intoxication, 13 (59%) were in the non-survivor group and 9 (41%) were in the survivor group. While the rate of invasive mechanical ventilation needed before the ICU was 55.6% in the survivor group, it was 100% in the non-survivor group, and there was a statistically significant difference between them (p<0.017). In the non-survivor patient group, blood HCO3 and pH levels were found to be significantly lower after ICU admission (p=0.002, p=0.008). At the same time, blood creatinine, potassium, and total bilirubin levels were significantly higher (p=0.002, p=0.007, p<0.035). Acute physiology and chronic health evaluation-II and sequential organ failure assessment scores after ICU admission were also significantly higher in the non-survivor group than in the survivor group (p=0.005, p=0.035). Conclusion: It was determined that in patients who died due to methyl alcohol intoxication, deeper metabolic acidosis and irreversible multiorgan failure developed during the period until ICU admission. The acute physiology and chronic health evaluation-II and sequential organ failure assessment scores were both effective in predicting mortality.
- Subjects
MORTALITY risk factors; RISK assessment; HYDROGEN-ion concentration; ALCOHOLIC intoxication; CREATININE; POTASSIUM; QUESTIONNAIRES; MULTIPLE organ failure; RETROSPECTIVE studies; BICARBONATE ions; BILIRUBIN; METHANOL; INTENSIVE care units; ARTIFICIAL respiration; APACHE (Disease classification system); ACIDOSIS; DISEASE complications
- Publication
Medical Journal of Bakirkoy, 2024, Vol 20, Issue 1, p48
- ISSN
1305-9319
- Publication type
Article
- DOI
10.4274/BMJ.galenos.2023.2023.1-8