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- Title
COMPARATIVE STUDY BETWEEN PLATELET RICH FIBRIN (PRF) AND NORMAL SALINE DRESSINGS FOR THE TREATMENT OF CHRONIC NON-HEALING ULCERS OF LOWER LIMB.
- Authors
KRISHNA, CHERUVU; RATNA KISHORE, SAVALAM BUJJITHA; SIMHADRI, SIRIPURAPU; VIJAYA, PAETTA
- Abstract
BACKGROUND As a chronic disease, venous leg ulcers can be treated in a number of ways. One of the more recent techniques is platelet-rich fibrin (PRF), which improves wound healing by containing fibroblast growth factor (GF), vascular endothelial GF, and platelet-derived GF. The potential of platelet-rich fibrin to promote healing in patients with lower extremity ulcers that do not heal over time was evaluated. AIM To determine the efficacy of PRF for management in chronic non healing ulcers of lower limb. MATERIALS AND METHODS Preliminary data were obtained from this prospective comparative study.25 cases were treated with PRF and 25 controls were treated with saline dressings. Age groups taken into consideration from 18 to 60 years. Initial ulcer size was less than 9 cm in longest dimension. Each PRF was placed and secondary dressing done and removed after 1 week. RESULTS Patients were followed Percentage reduction in the wound size is 84.55% in patients treated with PRF and 14.26% in patients with saline dressings weekly for 6 weeks. CONCLUSION PRF shows significant result for healing of chronic ulcers.
- Subjects
PLATELET-rich fibrin; FIBROBLAST growth factors; ULCERS; LEG ulcers; HEALING
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 6, p622
- ISSN
0975-3583
- Publication type
Article