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- Title
Assessment of Insulin Resistance with Two Methods: HOMA-IR and TyG Index in Iranian Obese Women.
- Authors
Mohammadabadi, Fahimeh; Vafaiyan, Zahra; Hosseini, Seyed Mehran; Aryaie, Mohammad; Eshghinia, Samira
- Abstract
Objective: The aim of the present study is assessment of insulin resistance (IR) in obese women by TyG-Index and compared with the HOMA-IR index. Materials and Methods: This cross-sectional study was performed on 61 obese women aged 18-45 years. Weights, height, waist circumference (WC) were measured and body mass index (BMI) was calculated and recorded. A sample of fasting serum was collected to determine the glucose, triglyceride, insulin, total cholesterol, HDL-C and LDL-C concentration. HOMA-IR and TyG-Index were calculated as markers of insulin resistance. Results: The mean age of the precipitants was 32.5 ±0.79 years old and the mean weight was 86.0±1.7 Kg. The number of people with IR who determined by HOMA and TyG index were 21(34%) and 36(61%), respectively. There was a significant relationship between HOMA-IR and TyG Index, r= 0.044 (P<0.001). Conclusion: TyG index represents a useful and accessible tool for assessment of IR instead HOMA_IR in Iranian population, but more researches with greater sample size and via gold standard lab test need to evaluate the specificity and sensitivity of this new method.
- Subjects
INSULIN resistance; HOMEOSTASIS; OBESITY in women; BODY mass index; TRIGLYCERIDES; WAIST circumference; IRANIANS; DISEASES
- Publication
Iranian Journal of Diabetes & Obesity (IJDO), 2014, Vol 6, Issue 1, p23
- ISSN
2008-6792
- Publication type
Article