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- Title
Primary Hepatic Neuroendocrine Tumor after 4 years Tumor-free Follow-up.
- Authors
Lambrescu, Ioana Maria; Martin, Sorina; Cima, Luminita; Herlea, Vlad; Badiu, Corin; Fica, Simona
- Abstract
Background: A primary hepatic neuroendocrine tumour (PHNET) is a very rare disease. The liver represents the preferential site for neuroendocrine tumors' metastases. Case presentation: A 45-year old Caucasian female who presented with nausea, vomiting, diarrhea, accompanied by diffuse abdominal pain was found to have on contrast-enhanced computer tomography an encapsulated, partially cystic liver mass. The patient underwent an uneventful left atypical hepatic resection. Histopatological and immunohistochemical examination revealed a slowly growing (G1) hepatic neuroendocrine tumour. Post surgery, the specific neuroendocrine markers (serum Chromogranin A and 24h urinary 5 hydroxy-indolacetic acid) were within normal range. Further functional imaging investigations were performed. No other lesions were found making probable the diagnosis of PHNET. The patient is presently after 4 years of follow-up with no local recurrence or distant metastases. Conclusions: The diagnosis of PHNET is a medical challenge that requires a thorough longterm follow-up in order to exclude an occult primary neuroendocrine tumour.
- Subjects
NEUROENDOCRINE tumors; LIVER disease diagnosis; LIVER diseases; NAUSEA; PATIENTS; DIAGNOSIS
- Publication
Journal of Gastrointestinal & Liver Diseases, 2015, Vol 24, Issue 2, p241
- ISSN
1841-8724
- Publication type
Case Study
- DOI
10.15403/jgld.2014.1121.242.4yrs