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- Title
Accelerometer-Derived "Weekend Warrior" Physical Activity and Incident Cardiovascular Disease.
- Authors
Khurshid, Shaan; Al-Alusi, Mostafa A.; Churchill, Timothy W.; Guseh, J. Sawalla; Ellinor, Patrick T.
- Abstract
Key Points: Question: Does engagement in moderate to vigorous physical activity, with most activity concentrated within 1 to 2 days of the week (ie, a "weekend warrior" pattern), confer similar cardiovascular benefits to more evenly distributed physical activity? Findings: In an analysis of 89 573 individuals providing a week of accelerometer-based physical activity data, a weekend warrior pattern of physical activity was associated with similarly lower risks of incident atrial fibrillation, myocardial infarction, heart failure, and stroke compared with more evenly distributed physical activity. Meaning: Increased activity, even when concentrated within 1 to 2 days each week, may be effective for improving cardiovascular risk profiles. Importance: Guidelines recommend 150 minutes or more of moderate to vigorous physical activity (MVPA) per week for overall health benefit, but the relative effects of concentrated vs more evenly distributed activity are unclear. Objective: To examine associations between an accelerometer-derived "weekend warrior" pattern (ie, most MVPA achieved over 1-2 days) vs MVPA spread more evenly with risk of incident cardiovascular events. Design, Setting, and Participants: Retrospective analysis of UK Biobank cohort study participants providing a full week of accelerometer-based physical activity data between June 8, 2013, and December 30, 2015. Exposures: Three MVPA patterns were compared: active weekend warrior (active WW, ≥150 minutes with ≥50% of total MVPA achieved in 1-2 days), active regular (≥150 minutes and not meeting active WW status), and inactive (<150 minutes). The same patterns were assessed using the sample median threshold of 230.4 minutes or more of MVPA per week. Main Outcomes and Measures: Associations between activity pattern and incident atrial fibrillation, myocardial infarction, heart failure, and stroke were assessed using Cox proportional hazards regression, adjusted for age, sex, racial and ethnic background, tobacco use, alcohol intake, Townsend Deprivation Index, employment status, self-reported health, and diet quality. Results: A total of 89 573 individuals (mean [SD] age, 62 [7.8] years; 56% women) who underwent accelerometry were included. When stratified at the threshold of 150 minutes or more of MVPA per week, a total of 37 872 were in the active WW group (42.2%), 21 473 were in the active regular group (24.0%), and 30 228 were in the inactive group (33.7%). In multivariable-adjusted models, both activity patterns were associated with similarly lower risks of incident atrial fibrillation (active WW: hazard ratio [HR], 0.78 [95% CI, 0.74-0.83]; active regular: 0.81 [95% CI, 0.74-0.88; inactive: HR, 1.00 [95% CI, 0.94-1.07]), myocardial infarction (active WW: 0.73 [95% CI, 0.67-0.80]; active regular: 0.65 [95% CI, 0.57-0.74]; and inactive: 1.00 [95% CI, 0.91-1.10]), heart failure (active WW: 0.62 [95% CI, 0.56-0.68]; active regular: 0.64 [95% CI, 0.56-0.73]; and inactive: 1.00 [95% CI, 0.92-1.09]), and stroke (active WW: 0.79 [95% CI, 0.71-0.88]; active regular: 0.83 [95% CI, 0.72-0.97]; and inactive: 1.00 [95% CI, 0.90-1.11]). Findings were consistent at the median threshold of 230.4 minutes or more of MVPA per week, although associations with stroke were no longer significant (active WW: 0.89 [95% CI, 0.79-1.02]; active regular: 0.87 [95% CI, 0.74-1.02]; and inactive: 1.00 [95% CI, 0.90-1.11]). Conclusions and Relevance: Physical activity concentrated within 1 to 2 days was associated with similarly lower risk of cardiovascular outcomes to more evenly distributed activity. This study examines associations between an accelerometer-derived "weekend warrior" pattern (ie, most moderate to vigorous physical activity achieved over 1-2 days) vs similar physical activity spread more evenly and the risk of incident cardiovascular events.
- Subjects
PHYSICAL activity; CARDIOVASCULAR diseases; ATRIAL fibrillation; MYOCARDIAL infarction; HEART failure
- Publication
JAMA: Journal of the American Medical Association, 2023, Vol 330, Issue 3, p247
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.2023.10875