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- Title
Mycobacterium bovis infection in a horse with granulomatous enterocolitis.
- Authors
Sarradell, Javier E.; Alvarez, Julio; Biscia, Mariana; Zumarraga, Martin; Wunschmann, Arno; Armien, Anibal G.; Perez, Andres M.
- Abstract
A 2-year-old dappled Percheron horse had a wasting condition that did not respond to antibiotic treatments and ultimately resulted in death. Thickening of the wall of the large colon and enlargement of the mesenteric lymph nodes were observed at postmortem examination, along with the presence of pinpoint whitish foci in the liver. Microscopic examination of affected tissues revealed diffuse chronic granulomatous enterocolitis, granulomatous mesenteric lymphadenitis, and multifocal granulomatous hepatitis. The DNA extracted from paraffin-embedded intestinal and lymph node samples was analyzed using both a polymerase chain reaction (PCR) assay and PCR–restriction endonuclease analysis and demonstrated the presence of Mycobacterium bovis.
- Subjects
TREATMENT of horse diseases; MYCOBACTERIUM bovis; ANTIBIOTICS; ENTEROCOCCAL infections; LYMPHADENITIS; DIAGNOSTIC use of polymerase chain reaction; THERAPEUTICS
- Publication
Journal of Veterinary Diagnostic Investigation, 2015, Vol 27, Issue 2, p203
- ISSN
1040-6387
- Publication type
Article
- DOI
10.1177/1040638715571359