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- Title
Management of recurrent alveolar soft-part sarcoma of the tongue after external beam radiotherapy with iodine-125 seed brachytherapy.
- Authors
Meng, Na; Zhang, Xiaomeng; Liao, Anyan; Tian, Suqing; Ran, Weiqiang; Gao, Yang; Wang, Jun Jie
- Abstract
Background Alveolar soft part sarcoma (ASPS) is a rare type of soft tissue sarcoma. The infrequency of ASPS is such that it accounts for <1% of all soft tissue sarcomas and <0.1% of sarcomas concerning the head and neck, primarily those involving the orbit (48%) and tongue (25%). Traditional chemotherapy or radiotherapy of ASPS is often associated with poor outcome, even after comprehensive interventions. Methods and Results We performed iodine-125 (125I) seed brachytherapy under ultrasound guidance through a submandibular puncture in a 4-year-old boy with recurrent ASPS of the tongue. The prescription dose was 120 Gy; therefore, 35 125I seeds were implanted with 0.77 mCi per seed, the total amount of activity being 26.95 mCi. CT scans confirmed a complete response after the treatment. Conclusion Our patient now has a recurrent-free survival of >30 months, an amount of time longer than the median rate described in the literature. © 2014 Wiley Periodicals, Inc. Head Neck 36: E125-E128, 2014
- Subjects
ALVEOLAR soft part sarcomas; TONGUE cancer; CANCER chemotherapy; MEDICAL radiology; RADIOISOTOPE brachytherapy
- Publication
Head & Neck, 2014, Vol 36, Issue 12, pE125
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.23648