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- Title
The Tussle Between Mycobacteria and Host: To Eat or Not To Eat.
- Authors
Bhaduri, Asani; Misra, Richa; Dhamija, Neeru
- Abstract
Autophagy is a catabolic process of cellular homeostasis evolutionarily conserved in eukaryotes. To block infection of intracellular bacterial pathogens, metazoans deploy autophagy for pathogen clearance through phago-lysosome formation and specific bactericidal peptides. Although an array of research have publicized the host regulatory factors, the function of bacterial effectors are yet to be understood in detail. In this article, we focus on the autophagic response to one of the most successful intracellular bacteria Mycobacterium tuberculosis.
- Subjects
AUTOPHAGY; REGULATION of cell growth; HOMEOSTASIS; EUKARYOTES; LYSOSOMES
- Publication
Indian Journal of Microbiology, 2015, Vol 55, Issue 4, p456
- ISSN
0046-8991
- Publication type
Article
- DOI
10.1007/s12088-015-0541-9