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- Title
Trapping of 134CS+ in frog skin epithelium as a function of short circuit current.
- Authors
Ussing, Hans H.; Lind, Fritze; Ussing, H H; Lind, F
- Abstract
In the sodium/potassium pump of the isolated frog skin epithelium, 134CS+ can to a certain degree replace potassium. If 134CS+ in almost a carrier-free amount is added to the solution bathing the inside of the frog skin in an Ussing chamber, there will be an uptake of 134 CS+ into the epithelium cells which is proportional to the short circuit current. Transepithelial flux of 134CS+ in leaky epithelia, for instance small intestine and frog skin glands, indicates a paracellular pathway. The consequences of these findings for the recycling-theory are discussed.
- Subjects
EPITHELIUM; FROGS; SKIN; SMALL intestine; POTASSIUM; ELECTRIC currents
- Publication
Kidney International, 1996, Vol 49, Issue 6, p1568
- ISSN
0085-2538
- Publication type
journal article
- DOI
10.1038/ki.1996.226