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- Title
Gastric Bypass in an Adolescent with Obesity, Insulin Resistance, and Type 1 Diabetes.
- Authors
Stefater, Margaret A.; Marks, Brynn E.
- Abstract
In addition to cell autoimmunity, patients with T1D and obesity have insulin resistance [[2]]. Whereas type 2 diabetes (T2D) is characterized by insulin resistance, type 1 diabetes (T1D) is defined by autoimmune-mediated cell destruction resulting in insulin deficiency. More limited reductions in A1c in patients with T1D, as compared to T2D, may reflect insulinopenia which limits the insulinotropic effect of incretins that is thought to improve glycemia in patients with T2D after BS [[10]]. This case illustrates the combination of insulin resistance and insulin deficiency characteristic of patients with T1D and obesity who have so-called double diabetes or type 1.5.
- Subjects
GASTRIC bypass; TYPE 1 diabetes; ADOLESCENT obesity; INSULIN resistance; TYPE 2 diabetes; HYPERGLYCEMIA
- Publication
Obesity Surgery, 2021, Vol 31, Issue 5, p2298
- ISSN
0960-8923
- Publication type
Letter
- DOI
10.1007/s11695-020-05190-z