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- Title
One-pot, solvent-free synthesis of α-aminonitriles under catalysis by magnesium bromide ethyl etherate.
- Authors
Mojtahedi, Mohammad M.; Abaee, M. Saeed; Abbasi, Hassan
- Abstract
A three-component, efficient, and facile procedure has been developed for the synthesis of α-aminonitriles from aldehydes, amines, and trimethylsilyl cyanide using a catalytic amount of magnesium bromide ethyl etherate in the absence of solvent. Rapid formation of products is observed at room temperature in a one-pot procedure under very mild conditions giving excellent yields of the title compounds.
- Subjects
AMINES; ALDEHYDES; CYANIDES; ETHER (Anesthetic); SOLVENTS; ORGANIC compounds
- Publication
Canadian Journal of Chemistry, 2006, Vol 84, Issue 3, p429
- ISSN
0008-4042
- Publication type
Article
- DOI
10.1139/V06-024