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- Title
Quantitative description of dialysis treatment: A dialysis index.
- Authors
Babb, Albert L.; Strand, Michael J.; Uvelli, David A.; Milutinovic, Jovan; Scribner, Belding H.
- Abstract
In this article, the author presents information on a dialysis index. The dialysis index which, in a single number, expresses the middle molecule removal for any patient/dialyzer combination. The dialysis index is an indicator of the effectiveness of removal of middle molecular weight substances. In the present state of development of the dialysis index, the molecular weight of the hypothetical marker solute has been chosen to correspond to that of a middle molecule represented by vitamin B12 which has a molecular volume of 1470 cm³/g-mole. The calculated weekly amount of the marker solute removed is assumed to result from the combined effects of residual renal function plus diffusional and convective trans-membrane transport during dialysis. The minimum weekly amount removed is the least amount required to maintain a satisfactory clinical condition.
- Subjects
DIALYSIS (Chemistry); HEMODIALYZERS; PATIENTS; VITAMIN B12; BIOLOGICAL membranes; HYPOTHESIS; KIDNEY diseases
- Publication
Kidney International Supplement, 1975, Issue 2, pS-23
- ISSN
0098-6577
- Publication type
Article
- DOI
10.1111/1523-1755.ep17665846