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- Title
Polymorphism of the gene of angiotensin converting enzyme: lack of association with mood disorder.
- Authors
Pauls, J.; Bandelow, B.; Rüther, E.; Kornhuber, J.
- Abstract
Summary. The insertion/deletion polymorphism of the gene of angiotensin-converting enzyme (ACE) was investigated in a case-control study including 169 patients with suffering from either bipolar disorder type I or unipolar recurrent major depression (DSM-IV) and 169 healthy controls. No significant association was found with bipolar disorder type I or unipolar recurrent depression and the polymorphism of the ACE gene. A previously reported genetic association (Arinami et al., 1996) was not confirmed by the present study.
- Subjects
AFFECTIVE disorders; ANGIOTENSIN converting enzyme; BIPOLAR disorder; GENETIC polymorphisms; PEPTIDASE; PROTEOLYTIC enzymes; ANGIOTENSINS
- Publication
Journal of Neural Transmission, 2000, Vol 107, Issue 11, p1361
- ISSN
0300-9564
- Publication type
Article
- DOI
10.1007/s007020070023