We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Aversive agents: Think twice. A case report on disulfiram‐induced mania.
- Authors
González‐Romero, María Fernanda; Martínez‐Ávila, José María; Moloney, Elizabeth; García‐Cabeza, Ignacio
- Abstract
We present a case of disulfiram‐induced mania in a patient with both alcohol use disorder (AUD) and psychostimulant use disorder (PUD), without a history of psychosis or mania. This acute presentation may be linked to the increased dopamine levels caused by disulfiram metabolism. Our patient developed manic symptoms 10 days after starting disulfiram, prescribed to treat the AUD. It should be noted that the symptoms resolved rapidly after disulfiram cessation during hospitalization. Disulfiram use is an effective treatment for alcohol dependence. However, there are safety concerns associated with it and it requires close monitoring, particularly in patients with a history of mania, psychosis, or psychostimulant use.
- Subjects
ALCOHOLISM; MANIA; DISULFIRAM
- Publication
Bipolar Disorders, 2024, Vol 26, Issue 4, p395
- ISSN
1398-5647
- Publication type
Article
- DOI
10.1111/bdi.13397