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- Title
Structure of large dsDNA viruses.
- Authors
Klose, Thomas; Rossmann, Michael G.
- Abstract
Nucleocytoplasmic large dsDNA viruses (NCLDVs) encompass an ever-increasing group of large eukaryotic viruses, infecting a wide variety of organisms. The set of core genes shared by all these viruses includes a major capsid protein with a double jelly-roll fold forming an icosahedral capsid, which surrounds a double layer membrane that contains the viral genome. Furthermore, some of these viruses, such as the members of the Mimiviridae and Phycodnaviridae have a unique vertex that is used during infection to transport DNA into the host.
- Subjects
DNA viruses; MOLECULAR structure; CYTOPLASM; VIRAL genomes; EUKARYOTES; MIMIVIRIDAE; PHYCODNAVIRIDAE; BIOLOGICAL membranes
- Publication
Biological Chemistry, 2014, Vol 395, Issue 7/8, p711
- ISSN
1431-6730
- Publication type
Article
- DOI
10.1515/hsz-2014-0145