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- Title
Analysis of the Kinetic Parameters of the Enzymatiс Catalysis of Esterifications in Hexane.
- Authors
Gamayurova, V. S.; Vorobiev, E. S.; Davletshina, G. A.; Rzhechitskaya, L. E.
- Abstract
Some of the kinetic parameters of esterifications of aliphatic acids and alcohols involving biocatalysts in nonaqueous media were analyzed using mathematical modeling. The kinetic equations were solved by the modified Runge–Kutta–Merson method, which provided the specified accuracy. The acids of the C3–C8 series were used as donors of acyl groups; the alcohols of the C4–C11 series, as acceptors; and nonimmobilized enzymes Lipozyme CALB and pancreatic lipase, as biocatalysts. An analysis of the calculated data made it possible to evaluate the occurrence of esterification, hydrolysis, and secondary esterification similar to autocatalysis in the system. Secondary esterification occurs because water that formed in primary esterification enters the hydration shell of the active site of enzyme, increasing its catalytic properties.
- Subjects
BIOCATALYSIS; CATALYSIS; BINDING sites; LIPASES; ACYL group; HEXANE; ALIPHATIC alcohols
- Publication
Kinetics & Catalysis, 2021, Vol 62, Issue 3, p360
- ISSN
0023-1584
- Publication type
Article
- DOI
10.1134/S0023158421030022