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- Title
Treatment and Predictors of Recurrent Internal Carotid Artery In-Stent Restenosis.
- Authors
Mihály, Zsuzsanna; Vértes, Miklós; Entz, László; Dósa, Edit
- Abstract
Purpose: We aimed to examine the effectiveness of different therapeutic options for and to identify the possible risk factors of recurrent internal carotid artery (ICA) in-stent restenosis (ISR). Methods: Forty-six ICA ISRs, which were reintervened at least once, were retrospectively analyzed regarding clinical and imaging characteristics, as well as invasive treatment type (percutaneous transluminal angioplasty [PTA] with a plain balloon, PTA with a drug-eluting balloon [DEB], re-stenting) used. Results: The median follow-up was 29.5 months (IQR, 8.5-52.8 months) in patients who underwent reintervention for ICA ISR. Stent occlusion occurred in 3 patients (6.5%). One ISR recurrence was noted in 10 patients (21.7%); reintervention was carried out in 7 cases (7/10 [70%]; PTA, N = 5; PTA with a DEB, N = 1; re-stenting, N = 1), while 3 patients (3/10; 30%) received best medical treatment. Two ISR recurrences were observed in 3 patients (6.5%); all of them underwent reintervention (PTA, N = 1; PTA with a DEB, N = 2). Three ISR recurrences were seen in 1 patient (2.2%), who was treated with PTA. No recurrence was observed in those patients, who had DEB treatment. Multiple logistic regression analysis revealed statin therapy to be a protective factor against recurrent ISR (OR, 0.17; 95% CI, 0.03-0.84; P =.029). Conclusion: Our study suggests that PTA with a DEB is the most effective for the treatment of recurrent ISR, and confirms the importance of statin use in patients who have had a carotid reintervention.
- Subjects
CAROTID artery; STATINS (Cardiovascular agents); CONFIDENCE intervals; MULTIPLE regression analysis; SURGICAL stents; RETROSPECTIVE studies; CORONARY restenosis; DISEASE relapse; DESCRIPTIVE statistics; ODDS ratio
- Publication
Vascular & Endovascular Surgery, 2021, Vol 55, Issue 4, p374
- ISSN
1538-5744
- Publication type
Article
- DOI
10.1177/1538574421993716