We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Distribution and molecular characteristics of rickettsiae found in ticks across Central Mongolia.
- Authors
Boldbaatar, Bazartseren; Rui-Ruo Jiang; von Fricken, Michael E.; Lkhagvatseren, Sukhbaatar; Nymadawa, Pagbajab; Baigalmaa, Bekhochir; Ya-Wei Wang; Anderson, Benjamin D.; Jia-Fu Jiang; Gray, Gregory C.
- Abstract
Background: Little is known regarding tick-borne diseases in Mongolia, despite having 26% of the population still living nomadic pastoral lifestyles. A total of 1497 adult unfed ticks: 261 Ixodes persulcatus, 795 Dermacentor nuttalli, and 441 Hyalomma asiaticum, were collected from three ecologically distinct regions in Central Mongolia. Tick pools (n = 299) containing ~5 ticks each, were tested for Rickettsia and Tick-borne encephalitis virus (TBEV) using nested polymerase chain reaction, reverse transcription-PCR, and quantitative real-time RT-PCR. Results: Assays yielded pooled prevalence of 92.5% (49/53) and 1.9% (1/53) for pooled I. persulcatus testing positive for "Candidatus Rickettsia tarasevichiae" and TBEV, respectively, while Rickettsia raoultii was found in 72.8% (115/158) of pooled D. nuttalli samples. When calculating a maximum likelihood estimation, an estimated 46.6% (95% CI: 35.2-63.6%) of I. persulcatus ticks in the pooled sample were infected with "Candidatus R. tarasevichiae". Conclusions: Both "Candidatus R. tarasevichiae" and R. raoultii are recognized as emerging tick-borne pathogens, with this being one of the first reports of "Candidatus R. tarasevichiae" in Mongolia. Given that "Candidatus R. tarasevichiae" shares the same vector (I. persulcatus) as TBEV, and infections may present with similar symptoms, Mongolian physicians treating suspected cases of TBEV should include "Candidatus R. tarasevichiae" infection in their differential diagnosis and consider prescribing antimicrobial therapy.
- Subjects
RICKETTSIAS; TICK-borne diseases; ENCEPHALITIS viruses; PATHOGENIC microorganisms; POLYMERASE chain reaction
- Publication
Parasites & Vectors, 2017, Vol 10, p1
- ISSN
1756-3305
- Publication type
Article
- DOI
10.1186/s13071-017-1981-3