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- Title
The First Analog of Pyrimidine Nucleosides with Two Nucleobases and Two d-Ribofuranose Residues.
- Authors
Andreeva, O. V.; Saifina, L. F.; Belenok, M. G.; Semenov, V. E.; Kataev, V. E.
- Abstract
The reaction of 1,5-bis[1-(prop-2-yn-1-yl)uracil-3-yl]pentane with 2',3',5'-tri-O-acetyl-β-d-ribofuranosylazide followed by removing of acetyl protective groups with a solution of sodium methylate in methanol afforded 1,5-bis{[1-methyl(β-d-ribofuranosyl)-1H-1,2,3-triazole-4-yl]uracil-3-yl}pentane which is the first analog of pyrimidine nucleosides with two nucleobases and two d-ribofuranose residues.
- Subjects
PYRIMIDINE nucleosides; BASE pairs; ACETYL group; PENTANE; CLICK chemistry
- Publication
Russian Journal of Organic Chemistry, 2021, Vol 57, Issue 2, p292
- ISSN
1070-4280
- Publication type
Article
- DOI
10.1134/S1070428021020226