We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Assessment of Docetaxel- and Paclitaxel-Related Diffuse Parenchymal Lung Disease: Two Case Reports.
- Authors
Yilmaz, Gulcin; Çoban, Hikmet; Çolak, Mustafa; Şenel, Merve Yumrukuz; Erel, Fuat; Sarioglu, Nurhan
- Abstract
Previous studies have reported the development of hypersensitivity pneumonia, interstitial pneumonia and organized pneumonia, two parenchymal lung diseases that are clinically and radiologically interchangeable, secondary to docetaxel and paclitaxel (Taxane) use. Parenchymal lung diseases secondary to docetaxel treatment are rare, but may have serious and even fatal consequences, and any delay in diagnosis and treatment can result in a poor prognosis. Docetaxel treatment should be discontinued and corticosteroid therapy should be initiated as soon as lung involvement becomes a concern. We present here two different cases who developed diffuse parenchymal lung toxicity associated with Taxane use, considering the information in literature.
- Subjects
LUNG diseases; PULMONARY fibrosis; IDIOPATHIC interstitial pneumonias; DELAYED diagnosis; DOCETAXEL; PACLITAXEL
- Publication
Respiratory Case Reports, 2024, Vol 13, Issue 1, p29
- ISSN
2147-2475
- Publication type
Case Study
- DOI
10.5505/respircase.2024.87369