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- Title
Feasibility of percutaneous left atrial appendage closure using a novel LAmbre occluder in patients with atrial fibrillation: Initial results from a prospective cohort registry study.
- Authors
Chen, Shaojie; Schmidt, Boris; Bordignon, Stefano; Bologna, Fabrizio; Nagase, Takahiko; Tsianakas, Nikolaos; Perrotta, Laura; Chun, K. R. Julian
- Abstract
Abstract: Background: The LAmbre™ occluder is a novel device for percutaneous left atrial appendage closure (LAAC). The presented study aimed to report the initial experience in implantation of the novel LAmbre for LAAC in patients with nonvalvular AF. Methods: We conducted a prospective, observational, cohort registry study to evaluate the feasibility of percutaneous LAAC using the LAmbre system. Results: Thirty patients (15 female, mean age 77.6 ± 8.9 years) who had high risks of stroke and contraindications for oral anticoagulation were prospectively enrolled in this registry study. The mean CHA2DS2‐VaSc was 3.9 ± 1.5, and the mean HAS‐BLED score was 4.1 ± 1.0. Twenty (66.7%) patients had chicken‐wing LAA morphology. The implant success rate was 100%. The mean fluoroscopic time and procedure time were 3.5 ± 1.9 and 29.0 ± 10.1 minutes, respectively. No significant procedure‐related complications were observed during in‐hospital and acute clinical follow‐up. Conclusion: In this preliminary study, the LAmbre occluder showed an excellent implant success rate, favorable implant property, and very low incidence of complications. Larger sample, randomized studies are further warranted.
- Subjects
STROKE risk factors; ATRIAL fibrillation; REPORTING of diseases; LONGITUDINAL method; SURGICAL complications; EQUIPMENT &; supplies; DATA analysis software; DESCRIPTIVE statistics
- Publication
Journal of Cardiovascular Electrophysiology, 2018, Vol 29, Issue 2, p291
- ISSN
1045-3873
- Publication type
Article
- DOI
10.1111/jce.13385