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- Title
Predictive value of mild cognitive impairment for dementia: the influence of case definition and age.
- Authors
Baars MAE; van Boxtel MPJ; Dijkstra JB; Visser PJ; van den Akker M; Verhey FRJ; Jolles J
- Abstract
BACKGROUND/AIMS: In population studies, different mild cognitive impairment (MCI) definitions have been used to predict dementia at a later stage. This study compared predictive values of different MCI definitions for dementia, and the effect of age on the predictive values was investigated. METHODS: This study was conducted as part of an ongoing longitudinal study into the determinants of cognitive aging, the Maastricht Aging Study. RESULTS: MCI best predicted dementia when multiple cognitive domains were considered and subjective complaints were not (sensitivity: 0.66, specificity: 0.78). Age had a strong influence on the sensitivity of MCI for dementia (age 60-70 years: sensitivity = 0.56; age 70-85 years: sensitivity = 0.70). CONCLUSION: The inclusion of multiple cognitive domains and participants aged 70 years and older leads to the best prediction of dementia, regardless of subjective complaints.
- Publication
Dementia & Geriatric Cognitive Disorders, 2009, Vol 27, Issue 2, p173
- ISSN
1420-8008
- Publication type
Journal Article
- DOI
10.1159/000200465