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- Title
Preemptive analgesia with intravenous tramadol for postoperative pain management in patients undergoing inguinal hernioplasty: a randomized controlled trial.
- Authors
Fahim, Muhammad; Abbasi, Sadia Ijaz; Malik, Naveed Akhtar; Khan, Jahangir Sarwar; Hassan, Hamid; Khan, Muhammad Mussadiq
- Abstract
Pain is recognized to be a major source of post-operative morbidity and pain intensity peaks during first post-operative hours and in adequate management leads to several pathophysiological changes in pulmonary and cardiovascular systems. A variety of post-operative analgesic strategies ranging from simple analgesic agents administered orally to nerve blocks to combat this pain has been sought. A simpler strategy of pre-emptive analgesic agent may be more acceptable for both surgeons and patients as a reliable pain relief technique. This is a prospective, randomized, placebo-controlled trial to assess the effectiveness of pre-emptive analgesia using tramadol in reducing post-operative pain following inguinal hernioplasty. Objective:To compare the post-operativepain with and without administration of pre-emptive intravenous tramadol in patients undergoing inguinal hernioplasty. Patients and Methods: It was a Randomized, double-blinded, placebo-controlled study conducted at Surgical Unit - I of Holy Family Hospital, Rawalpindi conducted from January 2011 to June 2012. Group I patients received 100 mg of tramadol intravenously while group II patients received 4ml of normal saline (placebo) before start of inguinal hernioplasty. VAS ratings of pain 6 hours following inguinal hernioplasty was measured in both groups. Results: A total of 248 patients, 124 patients in each group were randomized. All patients were male. Mean age was 37.02 (SD=12.66) in group I, while it was 38.24 (SD=13.87) in Group II. VAS scores 6 hours aft er surgery range from 0 to 10. Mean VAS score 6 hours aft er surgery was 3.48, (SD=1.67) in patients who received Tramadol (Group I), while it was 6.40, (SD=1.68) in patients who received placebo i.e. normal Saline (Group II) and a p-value of less than 0.0001 Conclusion: This implies that the administration of tramadol before the start of the surgical procedures can produce effective post-operative analgesia.
- Subjects
POSTOPERATIVE pain treatment; ANALGESIA; TRAMADOL; DRUG efficacy; PATIENT safety
- Publication
Pakistan Journal of Surgery, 2016, Vol 32, Issue 3, p143
- ISSN
0258-8552
- Publication type
Article