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- Title
The mouse t complex distorter-3 (Tcd-3) locus and transmission ratio distortion.
- Authors
Silver, Lee M.; Buck, Christine
- Abstract
A novel central partial t haplotype was generated by screening for a recombination event between overlapping distal and proximal partial haplotypes. This haplotype contains just two elements Tcrt and Tcd-3t —involved in the t-specific transmission ratio distortion phenotype. Breeding analysis of males that carry this chromosome provides evidence that Tcd-3 is, indeed, a distorter locus and not a second responder. Furthermore, the data indicate that a single well-defined distorter locus is insufficient to overcome completely the self-destructive, low transmission ratio distortion phenotype expressed by the t allele at the t complex responder locus, although a small, but highly significant, effect was observed.
- Publication
Genetics Research, 1993, Vol 62, Issue 2, p133
- ISSN
0016-6723
- Publication type
Article
- DOI
10.1017/S0016672300031724