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- Title
The Role of Neutrophil to Lymphocyte Ratio in the Assessment and Rehabilitation of Knee Osteoarthritis Patients.
- Authors
FUGARU, OVIDIU-FLORIN; ȘERBĂNESCU, MIRCEA-SEBASTIAN; TRĂISTARU, MAGDALENA RODICA
- Abstract
Osteoarthritis (OA) is considered to be a real problem for many people. The last decade is characterized through an increased interest in using a non-specific, simply and readily available marker of inflammationneutrophil to lymphocyte ratio (NLR)-to predict various chronic diseases (gastrointestinal and colorectal cancers, lung cancer, cardiovascular events, sarcoidosis, arthritis). The aim of our study is to establish the correlation between NLR and other parameters of clinical and functional status in KOA patients and to compare the NLR values before and after rehabilitation program. 90 patients, aged 40 to 82 years, diagnosed with mild (8 patients), moderate (70 patients) and severe (12 patients) KOA, in accordance with Kellgren and Lawrence score. Statistical assessment showed different values for the erythrocyte sedimentation (ESR) rate at 1-hour, Visual Analogue Scale (VAS), and Lequesne index in the studied group. NLR regression was significant for ESR at 1 and 2 hours. As an independent diagnostic marker, NLR has limited value, however it can be considered an inexpensive additional biomarker for the diagnosis of KOA and for monitoring the rehabilitation program.
- Subjects
NEUTROPHIL lymphocyte ratio; KNEE osteoarthritis; KNEE pain; SARCOIDOSIS; BLOOD sedimentation; VISUAL analog scale; GASTROINTESTINAL cancer
- Publication
Current Health Sciences Journal, 2023, Vol 49, Issue 4, p546
- ISSN
2067-0656
- Publication type
Article
- DOI
10.12865/CHSJ.49.04.10