We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cell-targeted vaccines: implications for adaptive immunity.
- Authors
Ung, Trevor; Rutledge, Nakisha S.; Weiss, Adam M.; Esser-Kahn, Aaron P.; Deak, Peter
- Abstract
Recent advancements in immunology and chemistry have facilitated advancements in targeted vaccine technology. Targeting specific cell types, tissue locations, or receptors can allow for modulation of the adaptive immune response to vaccines. This review provides an overview of cellular targets of vaccines, suggests methods of targeting and downstream effects on immune responses, and summarizes general trends in the literature. Understanding the relationships between vaccine targets and subsequent adaptive immune responses is critical for effective vaccine design. This knowledge could facilitate design of more effective, disease-specialized vaccines.
- Subjects
VACCINE effectiveness; VACCINES; ADAPTIVE modulation; IMMUNITY; IMMUNOREGULATION
- Publication
Frontiers in Immunology, 2023, p01
- ISSN
1664-3224
- Publication type
Article
- DOI
10.3389/fimmu.2023.1221008