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- Title
HEPATIC STEATOSIS IN PATIENTS WITH CHRONIC VIRAL HEPATITIS C TREATED WITH DIRECT ACTING ANTIVIRALS.
- Authors
Gavril, Oana Irina; Esanu, Irina Mihaela; Zota, Ioana Madalina; Popa, Iolanda Valentina; Arhire, Lidia Iuliana; Tatarciuc, Diana; Mastaleru, Alexandra; Drugescu, Andrei; Gavril, Radu Sebastian; Graur, Mariana; Mitu, Florin
- Abstract
Hepatic steatosis is a frequent pathological finding in patients with chronic viral C infection (HCV) and can be independently associated with increased alcohol consumption, type 2 diabetes, obesity and hyperlipidemia. All these factors can lead to the development of hepatic steatosis in patients with HCV. There are several noninvasive techniques and scores used for diagnosing and quantifying liver steatosis. Successful eradication of HCV with interferon-free treatment regimens has been suggested to improve the level of hepatic steatosis. The precise mechanisms responsible for these beneficial effects are currently under investigation, but it is thought that the decrease in hepatic inflammation and viral replication contribute to the resolution of hepatic steatosis. Moreover, the overall enhancement in liver health and metabolic factors may also have a significant impact.
- Subjects
FATTY liver; CHRONIC hepatitis C; VIRAL replication; TYPE 2 diabetes; ANTIVIRAL agents
- Publication
Internal Medicine / Medicină Internă, 2023, Vol 20, Issue 2, p55
- ISSN
1220-5818
- Publication type
Article
- DOI
10.2478/inmed-2023-0247