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- Title
A ONE-POT SYNTHESIS OF 4-METHYLPYRANO[3,2-C]QUINOLIN-2,5[6H]-DIONES.
- Authors
Venkatesh Kumar, N.; Rajendran, S. P.
- Abstract
4-hydroxy-2-quinolone being endowed with both nucleophilic and electrophilic properties furnishes the dimeric quinoline in a base catalyzed self-condensation process. A one step synthesis, starting from 4-hydroxy-2-quinolone with ethyl acetoacetate and pyridine proceeded through the Michael addition, which was followed by cyclization, gave an angular isomer 4-methylpyrano[3,2-c]quinolin-2,5[6H]-dione. The reaction was then extended to synthesize further derivatives of angular pyrano quinolones. Structures of all the products have been established by spectral and elemental analysis data.
- Publication
Heterocyclic Communications, 2004, Vol 10, Issue 4/5, p289
- ISSN
0793-0283
- Publication type
Article