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- Title
IN VITRO ANTIOXIDANT ACTIVITIES OF α-AMINOPHOSPHONATES.
- Authors
LAHBIB, K.; ESSID, I.; TOUIL, S.
- Abstract
Phosphorus compounds are biologically active molecules and exhibit a wide range of applications in the area of industrial, agricultural and medicinal chemistry. In this context, a green synthetic approach was developed for the synthesis of α-Aminophosphonates 1 (a-k) in good yields through one-pot multi-component reaction. All synthesized compounds were screened for their in vitro antioxidant activity with different methods using 1,1-diphenyl-2- picrylhydrazyl (DPPH), hydroxyl radical (OH˙), ferrous reducing power (FRP) and ferrous ion chelating (FIC) abilities. α-Aminophosphonates showed significant antioxidant activity that could suggest them for other biological uses.
- Subjects
ANTIOXIDANTS; PHOSPHONATES; PHARMACEUTICAL chemistry; HYDROXYL group; FARM produce
- Publication
Archives de l'Institut Pasteur de Tunis, 2017, Vol 94, Issue 1-4, p53
- ISSN
0020-2509
- Publication type
Article