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- Title
Synergistic and antimicrobial effects of leaves oil (phoenix dactylifera) agonist gram negative bacteria.
- Authors
mlaghee Al-safi, Shatha Mousa; hasson Al-Shabaa, Kefah fadhil; AL-Zeiny, Saadia S. Mehdy; Baqir Al-Dhalimy, Aiman Mohammed
- Abstract
Antibiotic resistance is a significant issue that represent a global challenge. Hence, it has been urgent and crucial to find suitable interventions to control the spread of antibiotic resistant bacteria. Plants, on the other hand are considered as the main alternative to enhance or replace drug candidates. One of them in this context is the oily palm leaves methanolic extract. It has been found to exert antioxidant properties owing to its constituents (phenolic compounds) such as tannins and flavonoids. The study involved the determination of MIC and MBC along with the synergism effect induced by a range of concentrations of leaves oil. For E. coli, the MBC value was at a concentration of 100 mg/ml while highly resistant E. coli in concentration 50, 25, 12.5 and 6.25mg/ml. For salmonella the MBC value was at a concentration of 50 mg/ml while MIC at 200mg/ml. it can be concluded that the combination of leaves oils with antibiotics can be effective against resistant strains to traditional antibiotics.
- Subjects
GRAM-negative bacteria; DATE palm; DRUG resistance in bacteria; ESCHERICHIA coli; LINSEED oil; ROSEMARY
- Publication
Systematic Reviews in Pharmacy, 2020, Vol 11, Issue 11, p177
- ISSN
0975-8453
- Publication type
Article