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- Title
Gene Function is a Driver of Activin Signaling Pathway Evolution Following Whole-Genome Duplication in Rainbow Trout (Oncorhynchus mykiss).
- Authors
Richman, Jasmine A; Davis, Leah R; Phelps, Michael P
- Abstract
The genomes of plant and animal species are influenced by ancestral whole-genome duplication (WGD) events, which have profound impacts on the regulation and function of gene networks. To gain insight into the consequences of WGD events, we characterized the sequence conservation and expression patterns of ohnologs in the highly duplicated activin receptor signaling pathway in rainbow trout (RBT). The RBT activin receptor signaling pathway is defined by tissue-specific expression of inhibitors and ligands and broad expression of receptors and Co-Smad signaling molecules. Signaling pathway ligands exhibited shared expression, while inhibitors and Smad signaling molecules primarily express a single dominant ohnolog. Our findings suggest that gene function influences ohnolog evolution following duplication of the activin signaling pathway in RBT.
- Subjects
RAINBOW trout; CELLULAR signal transduction; ACTIVIN receptors; ACTIVIN; PLANT genomes
- Publication
Genome Biology & Evolution, 2024, Vol 16, Issue 5, p1
- ISSN
1759-6653
- Publication type
Article
- DOI
10.1093/gbe/evae096