We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Utility of 4D Flow MRI in Thoracic Aortic Diseases: A Literature Review of Clinical Applications and Current Evidence.
- Authors
Kenichiro Takahashi; Tetsuro Sekine; Takahiro Ando; Yosuke Ishii; Shinichiro Kumita
- Abstract
Despite the recent technical developments, surgery on the thoracic aorta remains challenging and is associated with significant mortality and morbidity. Decisions about when and if to operate are based on a balance between surgical risk and the hazard of aortic rupture. These decisions are sometimes difficult in elective cases of thoracic aortic diseases, including aneurysms and dissections. Abnormal wall stress derived from flow alterations influences disease progression. Therefore, a better understanding of the complex hemodynamic environment inside the aortic lumen will facilitate patient-specific risk assessments of complications, which enable clinicians to provide timely prophylactic interventions. Time-resolved 3D phase-contrast (4D flow) MRI has many advantages for the in vivo assessment of flow dynamics. Recent developments in 4D flow imaging techniques has led to significant advances in our understanding of physiological flow dynamics in healthy subjects and patients with thoracic aortic diseases. In this clinically focused review of thoracic aortic diseases, we demonstrate the clinical advances acquired with 4D flow MRI from published studies. We provide a systematic overview of key evidences and considerations regarding normal thoracic aortas, thoracic aortic aneurysms, aortic dissections, and thoracic aortas with prosthetic graft replacement.
- Subjects
THORACIC aneurysms; AORTIC aneurysms; AORTIC dissection; MAGNETIC resonance imaging; AORTIC rupture
- Publication
Magnetic Resonance in Medical Sciences, 2022, Vol 21, Issue 2, p327
- ISSN
1347-3182
- Publication type
Article
- DOI
10.2463/mrms.rev.2021-0046