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- Title
HOming in on arteriovenous fistula survival.
- Authors
Durante, W.; Lin, C.-C.
- Abstract
Vascular access failure is a major clinical problem for patients on hemodialysis, but therapeutic approaches aimed at improving arteriovenous fistula (AVF) dysfunction remain elusive. Using a murine AVF model, Juncos et al. demonstrate for the first time that the stress protein heme oxygenase-1 (HO-1) is induced in AVFs and that HO-1 is a critical determinant of AVF survival.Kidney International (2008) 74, 9–11. doi:10.1038/ki.2008.127
- Subjects
ARTERIOVENOUS anastomosis; BLOOD vessels; ARTERIOVENOUS fistula; MICROCIRCULATION; BLOOD filtration; HEAT shock proteins; HUMAN abnormalities
- Publication
Kidney International, 2008, Vol 74, Issue 1, p9
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/ki.2008.127