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- Title
mTOR Signaling: Recent Progress.
- Authors
Gargalionis, Antonios N.; Papavassiliou, Kostas A.; Papavassiliou, Athanasios G.
- Abstract
The article discusses the role of the mechanistic target of rapamycin (mTOR) in various biological processes and diseases. mTOR is a kinase that regulates processes such as translation, autophagy, and cell survival. Dysregulation of the mTOR pathway is implicated in cancer, neurological disorders, and cardiovascular diseases. The article also mentions the development of small-molecule compounds that target mTOR for therapeutic purposes. However, there are ongoing debates and controversies regarding the efficient targeting of mTOR.
- Subjects
HUMAN biology; BREAST; DRUG resistance in cancer cells; SOMATOMEDIN; CELL communication; SIGNALS &; signaling; HOMEOSTASIS
- Publication
International Journal of Molecular Sciences, 2024, Vol 25, Issue 5, p2587
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms25052587