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- Title
EVALUATION OF THE SPATIAL RESOLUTION IN MONTE CARLO-BASED SPECT/CT RECONSTRUCTION OF 111IN-OCTREOTIDE IMAGES.
- Authors
Wikberg, Emma; Essen, Martijn van; Rydén, Tobias; Svensson, Johanna; Gjertsson, Peter; Bernhardt, Peter
- Abstract
The purpose was to evaluate the spatial resolution in 111In-octreotide single-photom emission computed tomography (SPECT)/computed tomography (CT) imaging following reconstructions with three different ordered subset expectation maximizations (OSEM) reconstruction algorithms; attenuation corrected (AC) OSEM, AC OSEM with resolution recovery (ACRR OSEM) and Monte Carlo-based OSEM reconstruction (MC OSEM). SPECT/CT imaging of a triple line phantom containing 111In in air and water was performed. The spatial resolution, represented by the full width at half maximum (FWHM) of a line profile, was determined for each line, for X and Y direction and for all reconstructions. The mean FWHM was 12.2 mm (±standard deviation [SD] 3.7 mm) for AC OSEM, 9.3 mm (±SD 2.5 mm) for ACRR OSEM and 8.2 mm (±SD 2.0 mm) for MC OSEM. MC-based SPECT/CT reconstruction clearly improves the spatial resolution in 111In-octreotide imaging and since MC simulations can be performed for all photon energies MC OSEM has the potential to improve SPECT/CT imaging overall.
- Subjects
SPATIAL resolution; COMPUTED tomography; SINGLE-photon emission computed tomography; IMAGE reconstruction; COLLIMATORS; TOMOGRAPHY
- Publication
Radiation Protection Dosimetry, 2021, Vol 192, Issue 3/4, p319
- ISSN
0144-8420
- Publication type
Article
- DOI
10.1093/rpd/ncab055