Found: 35
Select item for more details and to access through your institution.
Cytotoxycity and antiplasmodial activity of phenolic derivatives from Albizia zygia (DC.) J.F. Macbr. (Mimosaceae)
- Published in:
- BMC Complementary Medicine & Therapies, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12906-019-2792-1
- By:
- Publication type:
- Article
Inosine triphosphate pyrophosphatase from Trypanosoma brucei cleanses cytosolic pools from deaminated nucleotides.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10149-4
- By:
- Publication type:
- Article
Antiparasitic Meroterpenoids Isolated from Memnoniella dichroa CF-080171.
- Published in:
- Pharmaceutics, 2023, v. 15, n. 2, p. 492, doi. 10.3390/pharmaceutics15020492
- By:
- Publication type:
- Article
New Compounds with Bioisosteric Replacement of Classic Choline Kinase Inhibitors Show Potent Antiplasmodial Activity.
- Published in:
- Pharmaceutics, 2021, v. 13, n. 11, p. 1842, doi. 10.3390/pharmaceutics13111842
- By:
- Publication type:
- Article
The nucleotidohydrolases DCTPP1 and dUTPase are involved in the cellular response to decitabine.
- Published in:
- Biochemical Journal, 2016, v. 473, n. 17, p. 2635, doi. 10.1042/BCJ20160302
- By:
- Publication type:
- Article
The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells.
- Published in:
- Biochemical Journal, 2014, v. 459, n. 1, p. 171, doi. 10.1042/BJ20130894
- By:
- Publication type:
- Article
On the catalytic mechanism of dimeric dUTPases.
- Published in:
- Biochemical Journal, 2013, v. 456, n. 1, p. 81, doi. 10.1042/BJ20130796
- By:
- Publication type:
- Article
Identification of a residue critical for the excision of 3′-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family.
- Published in:
- Nucleic Acids Research, 2009, v. 37, n. 6, p. 1829, doi. 10.1093/nar/gkp021
- By:
- Publication type:
- Article
Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 5, p. 1, doi. 10.1371/journal.pntd.0003781
- By:
- Publication type:
- Article
Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 5, p. 1, doi. 10.1371/journal.pntd.0003781
- By:
- Publication type:
- Article
Exposure of Trypanosoma brucei to an N-acetylglucosamine-Binding Lectin Induces VSG Switching and Glycosylation Defects Resulting in Reduced Infectivity.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003612
- By:
- Publication type:
- Article
Exposure of Trypanosoma brucei to an N-acetylglucosamine-Binding Lectin Induces VSG Switching and Glycosylation Defects Resulting in Reduced Infectivity.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003612
- By:
- Publication type:
- Article
Preclinical evaluation of strasseriolides A–D, potent antiplasmodial macrolides isolated from Strasseria geniculata CF-247,251.
- Published in:
- Malaria Journal, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12936-021-03993-8
- By:
- Publication type:
- Article
Preclinical evaluation of strasseriolides A–D, potent antiplasmodial macrolides isolated from Strasseria geniculata CF-247,251.
- Published in:
- Malaria Journal, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12936-021-03993-8
- By:
- Publication type:
- Article
<i>Trypanosoma brucei gambiense</i> Adaptation to Different Mammalian Sera Is Associated with <i>VSG</i> Expression Site Plasticity.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0085072
- By:
- Publication type:
- Article
Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei.
- Published in:
- Molecular Microbiology, 2016, v. 102, n. 3, p. 365, doi. 10.1111/mmi.13467
- By:
- Publication type:
- Article
Carbohydrate-binding agents act as potent trypanocidals that elicit modifications in VSG glycosylation and reduced virulence in Trypanosoma brucei.
- Published in:
- Molecular Microbiology, 2013, v. 90, n. 4, p. 665, doi. 10.1111/mmi.12359
- By:
- Publication type:
- Article
Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents.
- Published in:
- PLoS Neglected Tropical Diseases, 2019, v. 13, n. 2, p. 1, doi. 10.1371/journal.pntd.0007129
- By:
- Publication type:
- Article
Apurinic/apyrimidinic endonuclease genesfrom the Trypanosomatidae Leishmania major and Trypanosoma cruzi confer resistance to oxidizing agents in DNA repair‐deficient Escherichia coli.
- Published in:
- Nucleic Acids Research, 1999, v. 27, n. 3, p. 771, doi. 10.1093/nar/27.3.771
- By:
- Publication type:
- Article
DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools.
- Published in:
- Cellular & Molecular Life Sciences, 2020, v. 77, n. 8, p. 1645, doi. 10.1007/s00018-019-03250-x
- By:
- Publication type:
- Article
Collective and Diverted Total Synthesis of the Strasseriolides: A Family of Macrolides Endowed with Potent Antiplasmodial and Antitrypanosomal Activity.
- Published in:
- Angewandte Chemie, 2024, v. 136, n. 36, p. 1, doi. 10.1002/ange.202408725
- By:
- Publication type:
- Article
A nuclear orthologue of the dNTP triphosphohydrolase SAMHD1 controls dNTP homeostasis and genomic stability in Trypanosoma brucei.
- Published in:
- Frontiers in Cellular & Infection Microbiology, 2023, p. 1, doi. 10.3389/fcimb.2023.1241305
- By:
- Publication type:
- Article
Collective and Diverted Total Synthesis of the Strasseriolides: A Family of Macrolides Endowed with Potent Antiplasmodial and Antitrypanosomal Activity.
- Published in:
- Angewandte Chemie International Edition, 2024, v. 63, n. 36, p. 1, doi. 10.1002/anie.202408725
- By:
- Publication type:
- Article
Discovery of New Compounds Active against Plasmodium falciparum by High Throughput Screening of Microbial Natural Products.
- Published in:
- PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0145812
- By:
- Publication type:
- Article
Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models.
- Published in:
- PLoS Pathogens, 2016, v. 12, n. 9, p. 1, doi. 10.1371/journal.ppat.1005851
- By:
- Publication type:
- Article
Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi.
- Published in:
- PLoS Neglected Tropical Diseases, 2023, v. 17, n. 9, p. 1, doi. 10.1371/journal.pntd.0011592
- By:
- Publication type:
- Article
Design, Synthesis, and Evaluation of 5′-Diphenyl Nucleoside Analogues as Inhibitors of the Plasmodium falciparum dUTPase.
- Published in:
- ChemMedChem, 2011, v. 6, n. 10, p. 1816, doi. 10.1002/cmdc.201100255
- By:
- Publication type:
- Article
Modified 5′-Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase.
- Published in:
- ChemMedChem, 2011, v. 6, n. 2, p. 309, doi. 10.1002/cmdc.201000445
- By:
- Publication type:
- Article
Opening Opportunities for New Drugs Against Neglected Diseases.
- Published in:
- ChemMedChem, 2008, v. 3, n. 3, p. 371, doi. 10.1002/cmdc.200800036
- By:
- Publication type:
- Article
A novel calcium-dependent soluble inorganic pyrophosphatase from the trypanosomatid Leishmania major
- Published in:
- FEBS Letters, 2004, v. 560, n. 1-3, p. 158, doi. 10.1016/S0014-5793(04)00097-3
- By:
- Publication type:
- Article
Characterization of deoxyuridine 5′-triphosphate nucleotidohydrolase from Trypanosoma cruzi<sup>1</sup><FN ID="FN1"><NO>1</NO>The nucleotide sequence reported here appears in DDBJ and GenBank nucleotide sequence databases under the accession number U93211.</FN>
- Published in:
- FEBS Letters, 2002, v. 526, n. 1-3, p. 147, doi. 10.1016/S0014-5793(02)03158-7
- By:
- Publication type:
- Article
Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase
- Published in:
- FEBS Letters, 2002, v. 510, n. 3, p. 141, doi. 10.1016/S0014-5793(01)03238-0
- By:
- Publication type:
- Article
Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Leishmania major.
- Published in:
- Protein Science: A Publication of the Protein Society, 2001, v. 10, n. 7, p. 1426, doi. 10.1110/ps.48801
- By:
- Publication type:
- Article
Repurposing the Open Global Health Library for the discovery of novel Mpro destabilizers with scope as broad-spectrum antivirals.
- Published in:
- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1390705
- By:
- Publication type:
- Article
Validation of Plasmodium falciparum dUTPase as the target of 5′-tritylated deoxyuridine analogues with anti-malarial activity.
- Published in:
- Malaria Journal, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12936-019-3025-2
- By:
- Publication type:
- Article